two. Histamine Receptor Antagonism: Some sedatives, which include antihistamines, exert their sedative effects by blocking histamine receptors in the brain, especially H1 receptors. Histamine performs a job in wakefulness and arousal, so blocking its effects promotes sedation and sleepiness. Don’t combine sedatives alongside one another or with other medications https://sedativesdrugs08631.blog2freedom.com/33065051/strongest-sedatives-available-dosage-effects-risks